
What is the global burden of HIV among sex workers? How do sex worker HIV burdens compare to the general population? How does this vary by region?
How does the policy and social context shape sex workers’ HIV risk across geographic settings? How does this context influence the provision and coverage of HIV services?
To what extent can comprehensive HIV prevention at-scale among sex workers modify HIV transmission dynamics among sex workers and the general population?
What are the most cost-effective HIV prevention, treatment, and care interventions in the context of sex work? What combinations of services are most cost-effective?
Given this evidence, what are the implications for allocative efficiency in HIV prevention programs?
How does violence against sex workers affect their health and human rights and HIV transmission dynamics among sex workers and the general population across settings?
What has been the role of sex worker leadership in promoting the human rights of and reducing the burden of and risks for HIV infection among sex workers across contexts?